important : 70 noun collocations | Collocation dictionary
Thus an alteration in the PG E 2 /F 2α ratio plays an importantrole in mediating IDO's effects on cell growth and morphology.
Serving the needy has been an importantpart of our mission.
This only goes to show you one thing, which happens to be the most importantthing to know about investing: Trying to game the market in the short-term is the definition of foolishness.
Whether lipid-lowering therapy would provide incremental benefit if initiated immediately following an acute coronary syndrome is an importantissue as the risk of a recurrent adverse cardiac events is much greater in patients with unstable coronary disease than in the stable setting.
As both MMPs and COX-2 are importantfactors in tumor development [ 48, 49] IDO's role in tumorigenesis bears investigating.
Thus a potentially importantaspect of our work is the combination of motif discovery from modules via Gibbs sampling and generalization to the entire genome with Ahab.
Most of these tests are maintained in different locations and measured annually, thus offering desirable opportunities to address two importantquestions: (1) How does the genes interact with environment?
The complexity of integrated cellular systems leads to an importantpoint, namely that the properties of complex biological processes cannot be analyzed or predicted based solely on a description of the individual components, and integrated systems based approaches must be applied [ 8].
There are a number of importantfeatures associated with this vector that are illustrated in Fig 2.
While the detailed mechanisms for such a novel mode of regulation still requires many additional studies, so far we observed several importantsteps that may contribute to SNIP1 degradation.
Comparison of reprogramming events between M I and M II oocytes would bring about importantinformation to understand the mechanisms of nuclear reprogramming in reconstructed embryos.
Although the nocturnin gene appears to encode a potentially importantcomponent of the circadian regulatory system in the Xenopus eye, its position within or downstream of the circadian clock mechanism has not been determined.
An importantconsideration at the outset of these studies concerned the possibility that ectopic hCAR expression or adenoviral transduction might affect the normal development and/or function of T cells.
Here's how YOU can make an importantdifference in someone's life... Dear Friends of Literacy, We all share a special interest in reading.
There are many other importantareas where children, families, the elderly and disabled need our help.
While inflammation is an importantelement in the defense against infection, it can also contribute to cholestatic biliary diseases and cholelithiasis.
And, while clinical trial safety endpoints may be considered less glamorous, MIRACL's most importantcontribution may have been that high-dose statin therapy was not associated with serious harm, despite its use in the unstable setting.
They have the potential to shape our world and make importantdecisions that will affect us all.
I am sure you will understand my writing to you once more about the importantwork of the American Cancer Society.
The most importantway to express that approval is through a financial contribution to support the work of the International Committee.
Collagen-gel contraction by SPARC-null fibroblasts is not compromised An importantevent during wound healing is the contraction of newly formed granulation tissue by fibroblasts to bring together the edges of the wound [ 1 ] .
It's not a new story but it is an importantone to consider.
There was no evidence suggesting that local drinking water is an importantsource of cryptosporidiosis in this population.
Implications for Myo1c activity The Ca 2+-dependent change in interaction of calmodulin with IQ1, the IQ domain closest to the motor domain, has importantimplications for Myo1c mechanochemical function.
We suspect that the most importantreason for the existence of a threshold signal is related to the formation of hybridization networks at these spots, which are also known as hyperpolymers [ 9 ] .
Development of the parallel plate flow chamber that simulates the conditions of physiologic flow has been an importanttool for dissecting the molecular events occurring between flowing leukocytes and endothelium [ 3 4 5 6 7 8 9 10 11 12 13 ] .
Making Nice As I understand it, when political scientists and sociologists refer to a society as "civil" they are citing the many importantfunctions that are performed by voluntary, intermediate institutions.
Aside from the major finding that screening did not reduce lung cancer mortality, several other importantfacts were uncovered.
I have already had occasion... to allude to an unfortunate habit which Prof. Skeat has of writing importantnotes without first consulting the full and accurate Indexes of N. & Q.; and I am very sorry to be obliged to renew my accusation.
Our results confirm that the importantchanges are indeed associated with subunit B.
Clinton, by contrast, is someone whose brain (unlike other parts of his body) seems always to be deployed in just the right places, shining light on an astonishing variety of importantmatters.
While rehospitalization for recurrent myocardial ischemia is an importantdeterminant of quality of life and health care costs, other important endpoints were not significantly affected (eg, death, myocardial infarction, resuscitated sudden cardiac death, worsening heart failure, need for coronary revascularization, etc).
No matter what we do that day, I always seem to learn an importantlesson."
While the LAT labels Vladimir Putin's visit to Chechnya a presidential "campaign-style tour" and the NYT calls it "unexpected," the Post relates that the new president had planned the trip months ago, long before Boris Yeltsin decided to step down (this importantdetail probably pushed the story off the Post 's front page).
Signifies one of the most importantstories of the day, according to that paper's editors.
Any or all of those assumptions may be wrong, of course, but in pointing to the discounting process in particular Greenspan did somethingimportant, which was get away from the simple idea of "irrationality" and move toward a more rigorous analysis of what's been happening.
The Dialectics of Dialects Dear Dennis, Judging from the responses to our exchange, we've skipped over some of the issuesimportant to most people, so perhaps we should go over dialects before we return to some recent headlines.
Along these lines, it has been shown that RSV activation of chemokine gene promoters involves multiple inducible transcription factors including AP-1 [ 52 53 ] , which is also a redox sensitive transcription factorimportant in chemokine gene expression [ 28 36 54 ] .
Although SPARC is expressed in fibroblasts and macrophages at wound sites [ 18 ] and functions in many processesimportant to wound repair, the role of SPARC in wound healing in a whole animal has not yet been studied.
Recent mutational analysis of recombinant PP5 has identified sequencesimportant in autoinhibition [ 19 ] .
Were you about to turn the virtual page, figuring that this couldn't be about anythingimportant?
Whatever the technical merits of the government's interpretation of the decree, you have to wonder whatimportant public interest will be served if the government's case succeeds.
Identification of over-represented sequence motifs in core promoters Core promoters are known to contain binding sites for proteinsimportant for transcription initiation, and our first analysis of the sequence content of our set of 1,941 core promoters was to assess the representation of two well-established core promoter sequence motifs, the initiator (Inr) and the TATA box.
The LEF-dependent luciferase assay in S2 cells is versatile, dynamic, rapid and can provide important clues about interactionsimportant for Wnt signaling.
The SMYD1 proteins are transcriptional regulatory proteins with chromatin-remodeling activitiesimportant in cardiac tissue, muscle and T lymphocytes [ 31 32 33 ] .
Giant vacuoles (structuresimportant for aqueous movement from the TM to canal lumen) were clearly observed indicating that SC was functional at P14 (Figure 3A).
In summary, practices that considered value important, that did not consider compatibilityimportant, that selected managed care software, that spent less than $10,000, or that provided learning time during implementation were more likely to perceive that the software had improved the financial analysis process than were other practices.
The grammar of the original language is kept, but a distinctive vocabulary develops, quite often when referring to activities or areasimportant to the subculture that the creating the language.
Why are formal complaintsimportant?
Why is supply chain collaborationimportant?
Why are Vitamins A and Eimportant?
The consequence of CD26 loss is unclear; CD26 modulates the action of many molecules including the chemotactic activity of some chemokineimportant for T-cell migration to skin [ 17 18 ] .
Fertiliser applicationimportant - to replace nutrients removed by stock and rabbits.
Why is decompositionimportant?
Is winning more businessimportant to you?
Cell culture and tumorigenesis model A weakly immunogenic lung cancer, Lewis lung carcinoma (3LL, H-2 b) obtained from ATCC (CRL-1642, LLC) was utilized for assessment of cytokinesimportant for SLC/CCL21 - mediated anti-tumor responses in vivo .
Two recent observations lend credence to the idea that genomes may be divided into domainsimportant for controlling the expression of groups of adjacent genes.
The customer views collected allows the purchase criteriaimportant for these customers to be revealed, so that the key purchase criteria can then be incorporated in a Customer Value questionnaire.
Why is a ge-free environmentimportant for organic agriculture and horticulture?
This will be achieved by ensuring everyoneimportant in each client's life is included in planning and decision-making.
What Gilder was pointing to here was in factimportant.
Is a light strong boardimportant to you?
Next: Lessons from Leigh: successes, mistakes, failuresimportant for others to learn from.
Histopathological Analysis Various histological featuresimportant for the differential diagnosis of A-GVHD were selected after review of literature [ 12 13 14 ] .
Before 9/11, Treasury did not consider terrorist financingimportant enough to mention in its national strategy for money laundering.
A few authors have noted that the fish consumption effect, despite being negatively associated with birth size, is small in comparison to other covariatesimportant for fetal growth and development [ 12 24 ] , which is more in keeping with our findings.
Is the controversyimportant?
Why is gender balanceimportant for the NZLS?
Why are saline soil habitatsimportant?
Is the image of the functionimportant for your family especially, or is it more a fun day to share with friends?