When he was twenty-six Ghirlandaio went to Rome to paint the Sixtine library, and then to San Gimignano, where he was assisted by Mainardi, who was to remain his most valuable ally in executing the large commissions which were to come to his workshop.

It is interesting to note that Ghirlandaio in his S. Trinità frescoes and Benedetto da Maiano in his S. Croce pulpit reliefs chose exactly the same scenes in the life of S. Francis: interesting because when Ghirlandaio was painting frescoes at San Gimignano in 1475, Benedetto was at work on the altar for the same church of S. Fina, and they were friends.

Liberation of San Gimignano.

Liberation of San Gimignano.