In them is an increased activity of the posterior lobe in association with enlargement and hyperfunction of the anterior, overgrowth is not so marked, and the individual is lean and mentally acute.

In general, the major endocrines, the pituitary, the adrenals, and the thyroid should hypertrophy and hyperfunction during pregnancy.

What happens when pituitary hyperfunction or superiority becomes underfunction or inferiority is precisely as Strachey has described so cleverly of the "ministering angel": the acrid, thin and keen degenerate every time into the amiable, fat and dull.

In the days of pituitary and thyroid hyperfunction we may be sure she would have been caustically and penetratingly ironical.