On the one hand, it is necessary to graduate very carefully the daily dose, never exceeding at the commencement the dose of two milligrammes (3/100 grain per diem) for adults, and never giving the arsenic upon an empty stomach.

On the other hand, it is necessary to gradually push the dose up to ten or twelve milligrammes (15/100 or 18/100) a day for adults, in districts where the malaria is very severe, giving the arsenic in such a way that there is never an accumulation of the drug in the stomach.

For the same approximation, the velocity of oscillation becomes five or six times greater, and, by the method employed, the last centigrammes and the milligrammes and their fractions are estimated directly, with immediate verification.

This difference, multiplied by the approximate value, in milligrammes, of each division of this dial (value given by the instrument) immediately gives the number of centigrammes and milligrammes that must be added to the weights already placed upon the pan of the balance in order to obtain an equilibrium, to about a half division of the lower dial.

This difference, multiplied by the approximate value, in milligrammes, of each division of this dial (value given by the instrument) immediately gives the number of centigrammes and milligrammes that must be added to the weights already placed upon the pan of the balance in order to obtain an equilibrium, to about a half division of the lower dial.

The value of each division of this dial varies from 3 to 10 milligrammes according as the balance shows 0.1 or 0.5 milligramme.

The value of each division of this dial varies from 3 to 10 milligrammes according as the balance shows 0.1 or 0.5 milligramme.

This number of divisions indicates the number of milligrammes and fractions of a milligramme by which it is necessary to shift the counterpoise on its arm in order to obtain a perfect equilibrium, which latter is verified by a simple reading.

This number of divisions indicates the number of milligrammes and fractions of a milligramme by which it is necessary to shift the counterpoise on its arm in order to obtain a perfect equilibrium, which latter is verified by a simple reading.