WHEN THE PITUITARY OVERACTS All grades of overaction of the pituitary exist.

If the overaction or excess of secretion begins in childhood or adolescence, that is, before puberty, there results a great elongation of the bones, so that a giant is the consequence.

If the overaction of the anterior happens after puberty, when the long bones have set, and can not grow longer, a peculiar diffuse enlargement of the individual occurs, especially of his hands and feet and head.

It is an interesting point to be noted that in these, as in those started by an overaction of the adrenal cortex, it is premature masculinity that is stimulated.

The pineal glands of a number of young bullocks were obtained and used for feeding, to see whether an overaction of the internal secretion could be produced.

A general reaction all along the line will accompany overaction, oversecretion, of one gland.

And like its variations, variations of their tone, development, reactivity, fatigability, and endurance may be traced to corresponding states of overaction, or underaction, and odd combinations of the different hormones.

The history of trade in the United States for the last three or four years affords the most convincing evidence that our present condition is chiefly to be attributed to overaction in all the departments of businessan over-action deriving, perhaps, its first impulses from antecedent causes, but stimulated to its destructive consequences by excessive issues of bank paper and by other facilities for the acquisition and enlargement of credit.

Extremes meet, and overaction steadfastly returns to the effect of non-action,bringing, however, the seven devils of disaster in its company.

The same senses are opened in delirium tremens, and entirely shut up again when the overaction of the cerebral heart, and the prodigious nervous congestions that attend it, are terminated by a decided change in the state of the body.

The chief embarrassments which at the moment exhibit themselves have arisen from overaction, and the most difficult task which remains to be accomplished is that of correcting and overcoming its effects.