The data obtained sofar on the action of PEDF on different cells may have not considered the presence of these cofactors in the media.
Sofar, several proteins have been found to interact with assembly intermediates of the 20S proteasome.
We have sofar identified two functional outcomes of the observed physical interaction between Smad1, HsN3 and Az in the signaling pathways of BMPs.
While the detailed mechanisms for such a novel mode of regulation still requires many additional studies, sofar we observed several important steps that may contribute to SNIP1 degradation.
At the time that we initiated this analysis, the only lipid-binding-impaired version of Boi1 that we had generated sofar was the KK mutant.
However, we have sofar failed to find COP1 homologues in Drosophila, C. elegans, or yeast, whose whole genome sequences are available.
BDM was recently shown not to inhibit any non-muscle myosins sofar tested, leaving the question of how it affects cells unanswered [ 9 10 ] .
The Id1 gene is different from any of the flowering genes isolated from Arabidopsis sofar.
In vertebrates 6 glypican family members belonging to the proteoglycan family have sofar been characterized [ 23 ] .
Sofar we have analyzed 68 genome quartets (see supplementary material).
Sofar, attempts to visualize NS1 production by Western blots have failed, presumably because of the low transfection efficiencies.
Sofar, the genes targeted for siRNA-mediated PTGS have been cellular in origin and thus, the mRNAs were transcribed in the nucleus by cellular DNA-dependent RNA polymerase.
Sofar this failure to complement has only been tested in the JFL101(pBS58) system, but the reduced expression of the mutant proteins suggests a possible dominant negative effect.
In all cases tested sofar, budding yeast enhancers have proved to be origin-specific; they stimulate only the origin with which they are normally associated in the chromosome [ 5, 6].
We focused our analysis on two positions which have already been shown to be involved in termination or readthrough in eukaryotes, but which have not been studied in mammalian cells sofar: the nucleotide preceeding the stop (-1) and the third nucleotide following the stop (+6) [ 15].
Several potential CD5 ligands have been reported sofar: the pan-B cell marker, CD72 [ 8]; an as yet unidentified lymphocyte specific inducible glycoprotein [ 9]; and, VH framework determinants on immunoglobulins [ 10].
Sofar, a satisfactory explanation for such strain differences has not been provided.
Although observed before [ 37] the projection of these fascicles has not been described sofar.
Sofar, Y-cells were assumed to be the most likely columnar GABAergic cell type [ 36, 37].
Results The zebrafish BDNF gene has at least four 5' non-coding exons The organization of all neurotrophin genes sofar examined is similar [ 28 29 ] .
Sofar internal non-coding exons have only been described in other neurotrophin genes, at first in the mouse NGF gene [ 30 31 ] and subsequently in the NT-3 gene [ 32 ] and more recently in the NT-4/5 gene [ 33 ] .
A significance of the results is that development of microsatellite markers is important not only for peanut researchers but also for peanut industry as the paucity of DNA markers in cultivated peanut has sofar precluded detailed genetic research on this crop.
Sofar, most of vessel remodeling studies are based on peripheral arteries, such as carotid and iliac arteries.
Sofar, little is known about the modulation role of TGF-β3 in vessel remodeling.
We feel that, since the meta-analysis is based on the data and not the written conclusions, that this comparison would only be meaningful when the conclusions are sofar-fetched as to cast doubt on the accuracy of the entire study.
Pretreatment with CAP impairs gp120 binding to coreceptors Data reported sofar suggest that the lethal hit to HIV-1 caused by CAP treatment involves the coreceptor binding site on gp120.
It is clear from the studies reported sofar, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.
Numerous studies have used a candidate gene approach to define genetic risk factors for stroke, but sofar results for several categories of candidate genes have been negative or conflicting.
Thus, results of the candidate gene approach have sofar failed to define genetic risk factors for stroke.
However, our findings sofar show that the achievable plasma levels of mhATF-BPTI are limited by adenoviral damage to the liver.
Sofar the mainstay of treatment for postpartum depression has rested with oral antidepressants, specifically the SSRI's.
This concern is characterized in the following quotes: "I was sofar out, drugging and using, I had a son that was born, he was born at five months, he weighted 1 lb.
Sofar he is doing okay.
[ 25 ] Although the adverse effects of mefloquine are common, and often serious and long lasting, and the drug has been widely used for over 20 years, no real attempts have sofar been made to investigate and explain these effects.
However, the variant polymerases and variant promoters that have sofar been identified are close in sequence to the wild-type.
The large sequence space that surrounds both polymerases and promoters has sofar prevented more sweeping searches for more diverse variants.
The structure of agonist 1 is entirely novel; it is the first RAR ligand described sofar with either a thiazole ring or a trifluoro group.
The observation that agonist 1 does not belong to any of the series of RAR ligands described sofar makes this compound particularly interesting for further development.
One of the molecules presented here constitute a good framework for the development of a novel series of RAR ligands very different from all structures described sofar.
In contrast to the ubiquitous DDRP, cellular RDRPs that are involved in PTGS sofar have been detected only in eukaryotes [ 1 26 ] .
Examination of the structure and multiple sequence alignments of bacterial β and β' subunits led to the identification of two additional, distinct domains, which sofar are not detectable in any proteins other than the DDRP and were accordingly designated Beta-Beta' Module 1 (BBM1, region 119-165, 1iw7 chain D) and Beta-Beta' Module 2 (BBM2, region 1109-1190, 1iw7 chain D) (Fig.
[ 8 ] Only one report of diabetic ketoacidosis associated with tacrolimus use in a patient without a prior history of diabetes has sofar been reported.