distress hardship trouble adversity misfortune poverty calamity privation destitution indigence suffering difficulties difficulty grief misery need trial tribulation want affliction burden deprivation impoverishment penury straits austerity beggary crunch disaster discomfort downer drag exigency hassle jam lack pickle pinch torment bummer catastrophe grievance hazard injury rigour rigor ruination scrape throe travail travails vicissitude worry tragedy blow setback misadventure mishap problem reverse ordeal woe mischance pain trauma sorrow accident failure torture heartache wretchedness vexation albatross agony contretemps upset knock ill anguish issue headache heartbreak unluckiness debacle cross inconvenience reversal casualty anxiety unhappiness sadness curse crucible persecution blunder infelicity complication hurt excruciation rack