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The Siblings With Ischemic Stroke Study (SWISS) is a multicenter affected siblingpair study with the aim of identifying chromosomal regions linked to ischemic stroke by using genome-wide scanning.
A total of 60 twin pairs interviewed, 52 aged matchedpairs from ages 14-42 years old met inclusion criteria.
Springtime means the islet of La Colonia becomes one of the most crowded bird habitats anywhere (more than 16,000 breedingpairs were identified in 1996).
The number of gene pairs represented in three, four and a greater number of genomes decayed rapidly, with highly conservedpairs forming the tail of the distribution (Fig.
Well, actually Humphrey Bogart and Katharine Hepburn did co-star in The African Queen , but few other equally rankedpairs ever worked together.
Protein sets (proteomes) from the followingpairs of complete genome sequences were compared in order to identify orthologous sequences: S. cerevisiae - S. pombe , S. cerevisiae - C. elegans , H. pylori strain 26695 - H. pylori strain J99, H. pylori strain 26695 - C. jejuni .
TSD scoring scheme The high-scoringpairs (HSPs) identified by bl2seq were scored heuristically by considering three factors: the HSP position in the 5' flank of the L1; the HSP position in the 3' flank of the L1; and HSP quality score.
To extend these more or less standard RNA folding algorithm conventions from a single sequence to an alignedpair of sequences, let us introduce some vectorial notation.
Alternatively, a covalent interaction may linkpairs of subunits.
A well-matedpair will spawn in the usual Cichlid manner: a smooth surface is cleaned off and the eggs are placed here and fertilized.
If you think that the practice in some Muslim countries of amputating the hand of a thief is harsh, beware of participating in horse shows in England, where there is no capital punishment but the issue arises every few years: A carriage and team of Cleveland Bay horses, driven by Mr Fred Pendlebury...[were] approaching the water obstacle during the cross-country section of the Harrods International Grand Prix when the leadingpair became confused, turned back and became entangled with the second pair.
Murray C. Zimmerman Whittier, California Feminist Stylistics Three decades after the reawakening of feminism, no field of scholarship remains unexamined by feminist analysis, a process rhetorician Gay D. Claiborne has defined as an effort to deconstruct the patterns of thinking that lead to a world-view of reality as consisting of oppositional, hierarchically-orderedpairs of things.
Members that I know about on the expedition were: Daniel Gemenis, John Atkinson, Joe Artts, Bruce Mutton and the above mentionedpair.
As with VPA, the pairwise contrasts show that the black and gray and brown and gray contrasts are significant, while the remainingpairs do not have significant mean differences (the same results is obtained using Sidak criteria).
Additional File 4 The difference in the α-SMA levels for two correspondingpairs non-palmoplantar and palmoplantar fibroblasts Absolute α-SMA levels may vary among fibroblasts from different individuals, but not the differences between paired keloid and palmar samples, and normal nonplantar and plantar samples, i.e.
The S. cerevisiae genome has also had a complete ancient genome duplication and 30% of the genes form duplicatepairs .
The operator wears a specially gradedpair of laser spectacles to protect his/her own sight.
Alternatively, the possibility that each word in an identifiedpair may be found at similar distances from a third conserved sequence element in all TCRs cannot be discounted.
By incorporatingpair-end sequence information, Cel2 and MGSCv3 contain around 47,000 scaffolds and around 43,000 supercontigs, respectively.
Covering the breasts was a joinedpair of black velvet, diamond-shaped patches, whose bottom points met the top points of a long black velvet skirt, of which the top edge plunged in one sharp V to the lace-covered navel in front, and swept diagonally back in a bigger V to the bottom of the lace-covered spine.
A table listingpairs of Pfam families that share more than 50% of their family members is provided as an additional file (see Additional File 1: [supp1.doc]).
The merging procedure is not permitted to mergepairs of partition points of the form ( B 1 , B 2 , l B ) and ( B 2 , B 1 , l B ).
If the fully sequenced BACs were not assembled in the correct order and orientation, we would expect to find regions of the genome where those end sequences fail to align to positions between 100 and 200 kb apart; such regions of misalignedpaired BAC end sequence were not observed in the final Release 3 chromosome arm assemblies.
Congratulations to Lisa and Patrick M who won the Manukau Mixedpairs at the indoor bowls tournament in March.
The results shown in Table 2were derived from a total of 519 structures consisting of 1451 lengths measured between neighboringpairs of structures (called links).
Thus any neighbouringpair of payoffs will overlap 24% of the time.
[ 14], in that the majority of overlappingpairs can be described as having a tail-to-tail (3' to 3') arrangement.
If I am again touched by the muse, ParingPairs may appear again.
We performedpaired t-tests on the RT-PCR values for the original set of fibroblast clones to test whether the average log change across cell strains differs from zero.
First, the decoys are generated by perturbingpairs of torsion angles by an amount δ.
The difference between the PM and MM oligonucleotides (probepair) was calculated, and the mean PM-MM intensity for each array was set to a constant value by linearly scaling array values.
Any of the instructions can access any RAM location either directly or indirectly through an index registerpair.
The same boxplots (Figure 7) for another set of 60 human U95A arrays consisting of 30 replicatepairs conveys similar information.
This result was compared with a previous study of the 200 most significant over-representedpairs [ 12, 33].
As we move along the showcase, these shoes begin more and more to resemblepairs of small sports cars and to suggest similar methods of marketing and design.
It is recommended, when performing cDNA microarray experiments with the standard two-fluorophore co-hybridization reactions, that all experiments and replicates be performed in fluorophore-reversedpairs.
Jenssen et al manually examined 1,000 randomly selectedpairs from the network of genes that had been created using this method: the proportion of incorrect (biologically meaningless) pairs were 40% for the low-weight category and 29% for the high-weight category.
Of the intersubunit signalingpair TrpEb_1 S178/TrpEa G181, S178 is not conserved within its own subfamily and equivalent residues seem to exist [ 26].
The parameters also gave a simulatedpair of genomes with an overall GC content of 47.25%.
Therefore, there are still too few cases with adequate sampling of intraspecific diversity for sister speciespairs to know how common paraphyly is, although a recent meta-analysis found that 17% of bird species deviated from mtDNA monophyly (Funk and Omland 2003).
q (theta) Indi is a strikingpair of stars of pale yellow and reddish hue, nicely visible in a small telescope.
The 19 th century British gardener Gertrude Jekyll was the first to suggestpairing ferns with daffodils, pointing out that just as the daffodil foliage begins to brown and die back, the fern hits its stride and covers the mess.
Maternal and gap gene factors together triggerpair rule gene expression in 7 alternating stripes, which in turn regulate segment polarity and homeotic gene expression in 14 stripes.
While many terminals also support EIA-423 is is almost like EIA-232 but is only 5 volts and somewhat higher speeds (without using twistedpair).
We have been fortunate to have access to two different assemblies, one of the whole genome, produced with a constrained assembler that utilizespaired-end information, and the other of BAC-sized intervals produced with an unconstrained assembler, phrap.
All of the secondary structure base pairs and a few of the tertiary structure base pairspredicted with covariation analysis [ 5 6 7 8 9 71 72 73 74 ] are present in the tRNA crystal structure [ 10 11 ] .
There appear to be some gene-specific interactions as suppression of swp73Δ by mig1Δ was stronger than the suppression observed for the other pairstested.
A probe pairconsists of a 25 base oligonucleotide that matches an mRNA sequence (perfect match, or PM probe) and an oligonucleotide with a mismatched base in the center (MM probe).
Most TC and DT pairsassociated with the same MGI genes have one or more sequences in common.
This is compatible with random, independent loss of gene pairs during evolution suggesting that, with the caveat of horizontal transfer, the number of gene pairsshared by three genomes could reflect the evolutionary distance between them.
The number of gene pairsrepresented in three, four and a greater number of genomes decayed rapidly, with highly conserved pairs forming the tail of the distribution (Fig.
Logistically, the collection of a large number of sibling pairsconcordant for stroke is a daunting task.
They comprise a tab-delimited text list of 989 identified conserved word-pair templates (Additional data file 1), a figure that shows that incorporation of conservation and word pairsprovided more informative average expression profiles (Additional data file 2), a figure that shows that regression models using conserved word pairs represented better fits to genome-wide expression data (Additional data file 3), and the underlying data for Figure 4that show associations between gene groups that share a conserved word-pair template with gene-expression changes (available as a zip.file, Additional data file 4; all files in TreeView, text tab-delimited, format).
We use "pairhidden Markov models" (pair-HMMs) (introduced in [ 18 ] ) and a "pair stochastic context free grammar" (pair-SCFG) (a natural extension of the pair-HMM idea to RNA structure) to produce three evolutionary models for "coding", "structural RNA", or "something else" (a null hypothesis).
The pairfinished first.
Primer sets and PCR conditions for direct sequencing Three primer pairsamplifying the coding portions of exons 1 and 3 and all of exon 2 were designed (Table 1).
The remaining base pairsform tertiary interactions that either span two sets of nested helices, forming a pseudoknot, or are involved in base triple interactions.
This pairfalls plumb in the middle of the Jooky target group: no dates, no sun, no sand.
Will exactly ten pairssell?
This hyperactive Tn 5 transposon is defined as any sequence flanked by the inverted 19 base pairrepeats known as mosaic ends (MEs).
Artur Dmitriev, another Russian gold medalist, also got negative press for his plunging neckline and wrapped sash, apparently too outrageous for pairsskating.
While the two keloid and palmar pairsdiffered in absolute α-SMA levels, the difference between paired keloid and palmar samples was statistically significant (p = 0.05) (not shown, please, see also additional file 4: Additional data #4.ppt).
Oligonucleotides are arranged in pairscorresponding to different regions of the target mRNA with multiple probe pairs.
"Local trawlers have repeatedly denied that they pair trawl within the dolphin's range, yet last week there was a deluge of sightings of boats pairtrawling between Port Waikato and Manukau harbour", says WWF Conservation Director Chris Howe.
One pairworked vigorously for many years resulting in a nest 20ft deep and 9 1/2ft wide!
Equality of survival distributions for the first and second treatment discontinuations was evaluated using the Wilcoxon matched-pairssigned-ranks test.
Distributions of identity percentage between probable orthologs from complete prokaryotic genomes Figure 2shows a sampling of the distributions of identity percentage between pairs of apparent orthologs identified as reciprocal best hits from a range of genome pairsseparated by varying phylogenetic distances.
The tree based on conserved gene pairsappeared to combine phylogenetic information with major effects of horizontal transfer of operons.
Looking at the four HG-U95A chip-pairs in Exp 2, with one chip of each pairscanned at "high gain" and the other at "low gain" PMT settings, the correlation coefficients across all probe sets ranged from 0.756 to 0.872 (Table 1).
While none of these potential ligands have been unequivocally shown to physiologically interact with CD5, these potential CD5 receptor/ligand pairssuggest that CD5 may play a role in T-B or B-1a-B cell-cell communication.
After many momentary, tantalising glimpses of the bird, which was feeding in company with a mate - I could hear them talking - one of the paircrossed the path, affording a good view, and corroborating what I had suspected as to species.
Intronic oligonucleotide primer pairsflanking the coding fragments were designed for both the genes using program primer 3 http://www.genome.wi.mit.edu/cgi-bin/primer/primer3.cgiusing the genomic sequences of SLC15A1 and GPC5 gene respectively.
The paircompleted clean sweeps of the A grade divisions.
If Rec12 protein is required for all (or most) meiotic recombination, then rec12 mutants might fail to produce a sufficient number of reciprocal exchanges to ensure that each chromosome pairreceives at least one crossover.
The correlation improved as the number of common probe pairsincreased (Figure 1).
The short cDNAs spotted on these arrays were produced with specific primer pairsobtained from Incyte Genomics, Inc. Use of these arrays for disc-to-disc comparisons also identified only a relatively small number of differentially expressed genes (data not shown).
This analysis produced two very large tables with 579 proposed 16S rRNA base pairsevaluated against six versions of the structure model and 1001 23S rRNA base pairs evaluated against five versions of the structure model.
Many of the tested antibody/antigen pairsallowed parallel detection of proteins in a microarray format at concentrations suitable for measurement of clinically important proteins in patient samples.
We still have pairsleft of our stylish club swimwear.
The Enrichment Factor (EF) is a parameter that represents the extent to which the Pfam pairsidentified by PCC1 within the cutoff range specified by C1 are over-represented in pools of Pfam pairs that could be identified by PCC2 within the cutoff range specified by C2 .
In addition, variation in the type of RNA/RNA base pairingoccurs with sequences in the highly variable middle section of micF RNA (positions 33-70, Figure 5).
Of course, the pairends up in the middle of every conflagration.
As for the soccer final, the Esala and Manoa Masi pairemerged as heroes in a game that could have gone to either side.
Here 13/16 introns lacked Watson-Crick pairing above the branch-point A and G:C was the downstream base pair whenever there was an upstream A:C, A:G or G:G. Additionally, no barley intron was found, in which the upstream Watson-Crick paircoincided with a downstream G:U or other weak pair.
Results Identification of predicted ORFs encoding replication-related proteins An ~11-kb contiguous genomic fragment from M. paratuberculosis was amplified and sequenced using 15 primer pairsdesigned from M. avium genomic sequence in the putative oriC region (Fig.
After the paircleared Immigration and Customs at Los Angeles International Airport, we do not know where they went.8They appear to have obtained assistance from the Muslim community, specifically the community surrounding the King Fahd mosque in Culver City, one of the most prominent mosques in Southern California.
The end is even sweeter, and pairsclasped hands: the grown-up hand and the kiddie hand; the black hand and the white hand, and so on.
After each clustering cycle, the centroids were combined with those identified in previous cycles, and replicate centroids were averaged: each centroid was compared to all other centroids in the set, and centroid pairscorrelated >0.9 were replaced by the average of the two vectors.
Each partition point has a reference to the paircoordinates ( A 1 , A 2 ) and the repeat length l. Each repeat corresponds to at least two partition points.
While the Globe 's photographer failed to capture the pairchoosing hydroponic tomatoes, we feel fairly confident that they did not buy any apples.