The general principle of this discovery may be described as follows: "The frequency of accidents, arising from the explosion of the fire-damp, or inflammable gas of the coal mines, mixed with atmospherical air, occasioned the formation of a committee at Sunderland, for the purpose of investigating the causes of these calamities, and of endeavouring to discover and apply a preventive.

A scientific investigator should be as proud of discovering a preventive for colds as a scheme of wireless telegraphy.

This cordial was very generally taken in the British provinces, under the various names of "bitters," "juleps," "morning-drams," "fogmatics," &c., according as the situation of each district appeared to require some particular preventive.

The man Gadley was meantime driving an active trade at the 'Three Pigeons,' whither the poor, possessed with the notion that spirits kept out the infection, were resorting more than ever, and he set at defiance all the preventives which doctors, overseer, and relieving officer were trying to enforce, with sullen oaths against interference.