Which preposition to use with upstairs

in Occurrences 10%

" Upstairs in his room he triumphantly opened his desk before them.

to Occurrences 2%

There was no upstairs to itonly one large room with a dirty curtain stretched across it.

at Occurrences 1%

Something to do with the experiments he is carrying on upstairs at this very moment, I expect."

Which preposition to use with  upstairs