Manco left three young sons, Sayri Tupac, Titu Cusi, and Tupac Amaru.

Sayri Tupac died in 1560, leaving two brothers; the older, Titu Cusi Yupanqui, illegitimate, and the younger, Tupac Amaru, his rightful successor, an inexperienced youth.

He was unsuccessful in his efforts to get Titu Cusi to go to Cuzco.

Apparently this ceremony "of the most profound resignation and reverence" was practiced in Chuquipalpa, close to Uiticos, in the reign of the Inca Titu Cusi.

Of course, as soon as the Inca Titu Cusi heard of it, he was greatly annoyed.

Friar Diego, particularly beloved by those Indians who came from the fever-stricken jungles in the lower valleys, was allowed to remain, and finally became a trusted friend and adviser of Titu Cusi.

In the year 1570, ten years after the accession of Titu Cusi to the Inca throne in Uiticos, a new Spanish viceroy came to Cuzco.

In the meantime the viceroy had picked out a Cuzco soldier, one Tilano de Anaya, who was well liked by the Inca, to try to persuade Titu Cusi to come to Cuzco.

Titu Cusi's illness was very serious.

The "remedies" were held by Titu Cusi's mother and her counselors to be responsible.

His half brother Titu Cusi becomes Inca. 1566.

Titu Cusi dies.

Here he lived three years and here, in 1560, he died an untimely death under circumstances which led his brothers, Titu Cusi and Tupac Amaru, to think that they would be safer in Uiticos.

Perhaps this was the place referred to by Ocampo, who says that the Inca Titu Cusi attended masses said by his friend Friar Diego in a chapel which is "near my houses and on my own lands, in the mining district of Puquiura, close to the ore-crushing mill of Don Christoval de Albornoz, Precentor that was of the Cuzco Cathedral.

In this he says: "and having arrived at the principal fortress, Guay-napucará ["the young fortress"], which the Incas had fortified, we found it defended by the Prince Philipe Quispetutio, a son of the Inca Titu Cusi, with his captains and soldiers.

Finally Rodriguez de Figueroa speaks expressly of two pairs of scissors he brought as a present to Titu Cusi.

Titu Cusi gives no definite clue, but the activities of Friar Marcos and Friar Diego, who came to be his spiritual advisers, are fully described by Calancha.

It was during Titu Cusi's reign that Friars Marcos and Diego marched over here with their converts from Puquiura, each carrying a stick of firewood.

Titu Cusi says he lived there many years during his youth.

Yet even then Titu Cusi was unwilling that they should live in the city, but ordered that the monks be given a dwelling outside, so that they might not witness the ceremonies and ancient rites which were practiced by the Inca and his captains and priests.

During their stay Titu Cusi, who had not wished to bring them here, got his revenge by annoying them in various ways.

Rodriguez de Figueroa, who came to seek an audience with Titu Cusi about 1565, says that he met Titu Cusi at a place called Banbaconas.

It would have been possible for Titu Cusi to bring Friar Marcos and Friar Diego to the village of Intihuatana near San Miguel, at the foot of the Machu Picchu cliffs.

In the interesting account of the last Incas purporting to be by Titu Cusi, but actually written in excellent Spanish by Friar Marcos, he says that his father, Manco, fleeing from Cuzco went first "to Vilcabamba, the head of all that province.

Titu Cusi was an illegitimate son of Manco.